Gas Chromatography



Quantum scientists have a wide breath of experience and knowledge in the application of Gas Chromatography (GC). Our GC group provides comprehensive analytical testing in support of active pharmaceutical ingredients (API), intermediates, raw materials, in-process samples and finished products. We have developed and validated numerous GC methods in support of assay, purity and impurity identification. And, have supported the development and validation of such methods for CMC.

Instrument Configurations

  • Flame Ionization, Thermal Conductivity and Electron Capture Detectors
  • Direct injection including cool on column injection
  • Static Headspace
  • Chemstation with Electronic Records and Signatures


The GC services provide an array of analytical testing capabilities including but not limited to:

  • Established Compendial methods (USP/NF, EP, JP, BP, FCC, ACS, etc)
  • Client supplied methods
  • Method Development, Validation, and Transfer (including protocol development and report generation)
  • USP <467> Residual Solvents Testing (including method evaluation, feasibility and development/validation studies, as needed)
  • Stability testing of Drug Substances and Drug Products
  • Chromatographic Purity
  • Assay
  • Chromatographic Limit Tests