Atomic Absorption and Emission Spectroscopy

Analysis by Flame Atomic Absoprtion Perkin Elmer 900F

Quantum has expansive capabilities for the analysis of heavy metals and elemental impurities. And, our scientists have a wide breath of experience and knowledge in the application of  atomic absorption and emission spectroscopy. We have over 25 years of experience in the use and application of these analytical techniques, and with the many sample preparation techniques, which include various wet digestion, ashing and closed vessel microwave digestion methods.  Our laboratories maintain a full complement of instrumental capabilities which include flame and graphite furnace atomic absorption (AAS), inductively coupled plasma-atomic emission (ICP-AES or ICP-OES) and inductively couple plasma-mass spectrometry (ICP-MS) instruments.  These capabilities allow us to perform testing not only using ICP-AES or ICP-MS for elemental impurities following USP <232>& <233>, ICH Q3D guidelines and FDA requirements, but also the many numerous compendial methods (i.e. USP, NF, FCC, EP, AOAC) that require flame  or graphite furnace AAS. Our Elemental group provides comprehensive analytical testing in support of pharmaceuticals, medical devices, personal care products, cosmetics, and consumer products. These include the testing of active pharmaceutical ingredients (API), intermediates, raw materials, in-process samples and finished products for heavy metals originating from process equipment, catalysts or found present naturally. We have successfully developed and validated numerous AAS and ICP methods in support of assay, such as for mineral sun screens or  fungistatic soaps, and impurity identification. And, have supported the development and validation of such methods for CMC and other regulatory submittals.